TACI is mutant in common variable immunodeficiency and IgA deficiency

Emanuela Castigli, Stephen A. Wilson, Lilit Garibyan, +4

Nature Genetics

Primary ImmunodeficiencyClinical ImmunologyImmunogeneticsAutoimmune DiseaseImmunodeficiencies +10

TACI and BAFF-R mediate isotype switching in B cells

Emanuela Castigli, Stephen A. Wilson, Sumi Scott, +6

The Journal of Experimental Medicine

ImmunologyImmune RegulationMolecular BiologyImmunologic MechanismImmune System +15

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

Micah J. Benson, Stacey R. Dillon, Emanuela Castigli, +4

The Journal of Immunology

Impaired IgA class switching in APRIL-deficient mice

Emanuela Castigli, Sumi Scott, Fatma Dedeoğlu, +5

Proceedings of the National Academy of Sciences

CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

Emanuela Castigli, Frederick W. Alt, Laurie A. Davidson, +4

Proceedings of the National Academy of Sciences

Lymphocyte DevelopmentImmunologyCd40- Cd40l InteractionsAntigen ProcessingImmunotherapy +14

The Binding Site for TRAF2 and TRAF3 but Not for TRAF6 Is Essential for CD40-Mediated Immunoglobulin Class Switching

Haifa H. Jabara, Dhafer Laouini, Erdyni N. Tsitsikov, +7

Immunity

Signal TransductionTraf6 Is EssentialImmunologyImmunodominanceBinding Site +7

Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation

Emanuela Castigli, Stephen A. Wilson, Abdallah Elkhal, +3

Journal of Allergy and Clinical Immunology

InflammationSignal TransductionCalcium ModulatorImmunologyImmunologic Mechanism +8

Mast cells regulate IFN-γ expression in the skin and circulating IgE levels in allergen-induced skin inflammation

Harri Alenius, Dhafer Laouini, Amy Woodward, +5

Journal of Allergy and Clinical Immunology

InflammationAllergyAtopic DermatitisImmune Cell DevelopmentMast Cell Disorder +11

Immunosuppressive activity of 13-cis-retinoic acid and prevention of experimental autoimmune encephalomyelitis in rats.

Luca Massacesi, Emanuela Castigli, Marco Vergelli, +4

Journal of Clinical Investigation

T-regulatory CellImmune RegulationImmunologyImmunologic MechanismImmunotherapy +18

An obligate role for T-cell receptor αβ+ T cells but not T-cell receptor γδ+ T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis

Amy Woodward, Jonathan M. Spergel, Harri Alenius, +6

Journal of Allergy and Clinical Immunology

InflammationAtopic DermatitisAdaptive Immune SystemImmune RegulationImmunology +13