APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

Elodie Belnoue, Maria Pihlgren, Tracy L. McGaha, +7

Blood

An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A  Binding Properties Promotes Neuroprotection and Glial Engulfment of A 

Oskar Adolfsson, Maria Pihlgren, Nicolas Toni, +18

Journal of Neuroscience

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy

Clara Theunis, Natàlia Crespo‐Biel, Valérie Gafner, +12

PLoS ONE

ImmunologyTau.p301l MiceNeuroinflammationAlzheimer's DiseaseVaccine Target +16

Resting Memory CD8+ T Cells are Hyperreactive to Antigenic Challenge In Vitro

Maria Pihlgren, Patrice Dubois, Martine Tomkowiak, +2

The Journal of Experimental Medicine

Adaptive Immune SystemT-regulatory CellImmunologyImmunodominanceAntigen Processing +14

Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

Andreas Muhs, David T. Hickman, Maria Pihlgren, +15

Proceedings of the National Academy of Sciences

ImmunologyImmunodominanceAntigen ProcessingLiposomal VaccinesImmunotherapy +17

CpG Oligodeoxynucleotides Can Circumvent the Th2 Polarization of Neonatal Responses to Vaccines But May Fail to Fully Redirect Th2 Responses Established by Neonatal Priming

Jiří Kovařík, Paola Bozzotti, Laurie Love-Homan, +5

The Journal of Immunology

Neonatal PrimingImmunologyImmunodominanceImmunologic MechanismImmunotherapy +17

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

Seung-Hye Lee, Claire E. Le Pichon, Oskar Adolfsson, +20

Cell Reports

Tau AntibodiesTau PathologyImmunologyCell DeathImmunologic Mechanism +20

Unresponsiveness to Lymphoid-Mediated Signals at the Neonatal Follicular Dendritic Cell Precursor Level Contributes to Delayed Germinal Center Induction and Limitations of Neonatal Antibody Responses to T-Dependent Antigens

Maria Pihlgren, Chantal Tougne, Paola Bozzotti, +4

The Journal of Immunology

Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response

Claire‐Anne Siegrist, Maria Pihlgren, Chantal Tougne, +8

Vaccine

VaccinationVaccine DevelopmentViral HepatitisImmunologyHepatitis +3

Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin

Mark Ultsch, Bing Li, Till Maurer, +13

Scientific Reports