Concepedia

A presenilin‐1/γ‐secretase cleavage releases the E‐cadherin intracellular domain and regulates disassembly of adherens junctions

Philippe Marambaud

The EMBO Journal · 2002 · 680 citations · 40 references

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References

40

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

, , +17

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

, , +12

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

, , +13

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

Peter Carmeliet, Maria Grazia Lampugnani, Lieve Moons et al. · Cell · 1999 · 1.3K citations · Full text

, , +13

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Gopal Thinakaran, David Borchelt, Michael K. Lee et al. · Neuron · 1996 · 1K citations · Full text

, , +3