A cell junction is a multiprotein complex at specialized regions of the plasma membrane that mediates adhesion, communication, and/or barrier formation between adjacent cells or between a cell and the extracellular matrix.
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JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA
Marilyn G. Farquhar, George E. Palade · The Journal of Cell Biology · 1963 · 3.6K citations · Full text
Life Sciences, Anatomy, Cell Biology +17
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations
Occludin: a novel integral membrane protein localizing at tight junctions.
Mikio Furuse, Tetsuaki Hirase, Masahiko Itoh et al. · The Journal of Cell Biology · 1993 · 2.5K citations · Full text
Nucleic acid junctions and lattices
Nadrian C. Seeman · Journal of Theoretical Biology · 1982 · 2.5K citations
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See also Cell Junctions | |
|---|---|
Junction Types | Gap Junctions Tight Junctions Adherens Junctions Tricellular Junctions |
Molecular Components | |
Biological Functions | Cell-cell Adhesion Epithelial Barrier Function Tissue Architecture Cell-matrix Adhesion Epithelial Apical-basal Polarity Fetal Organ Development |
Disease Relevance | Heart Failure Colorectal Cancer Cardiac Hypertrophy Signaling Cardiovascular Aging Pneumococcal Disease Inflammatory Bowel Disease |
Assembly Mechanisms | |