Concepedia

Target Immobilization as a Strategy for NMR-Based Fragment Screening: Comparison of TINS, STD, and SPR for Fragment Hit Identification

Masakazu Kobayashi, Kim Retra, Francis Figaroa, Johan G. Hollander, Eiso AB, Robert J. Heetebrij, Hubertus Irth, Gregg Siegal

SLAS DISCOVERY · 2010 · 40 citations · 21 references

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Concepts

References

21

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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Discovering High-Affinity Ligands for Proteins: SAR by NMR

Suzanne B. Shuker, Philip J. Hajduk, Robert Meadows et al. · Science · 1996 · 2K citations

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Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

Moriz Mayer, Bernd Meyer · Angewandte Chemie International Edition · 1999 · 1.6K citations

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A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

Susan L. McGovern, Emilia Caselli, Nikolaus Grigorieff et al. · Journal of Medicinal Chemistry · 2002 · 1K citations · Full text

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WaterLOGSY as a method for primary NMR screening: Practical aspects and range of applicability

Claudio Dalvit, Gianpaolo Fogliatto, Albert Stewart et al. · Journal of Biomolecular NMR · 2001 · 560 citations

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