Robert J. Heetebrij

TINS, Target Immobilized NMR Screening: An Efficient and Sensitive Method for Ligand Discovery

Sophie Vanwetswinkel, Robert J. Heetebrij, John van Duynhoven et al. · Chemistry & Biology · 2005 · 141 citations · Full text

Ligand Discovery, Biochemistry, Natural Sciences +9

New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy

Chris Molenaar, Jan‐Maarten Teuben, Robert J. Heetebrij et al. · JBIC Journal of Biological Inorganic Chemistry · 2000 · 115 citations

Microscopy, Natural Sciences, Novel Imaging Method +9

Calcium Ions Do Accelerate the DNA Binding of New Antitumor-Active Platinum Aminophosphonate Complexes

Marieke J. Bloemink, Jeroen J. H. Diederen, Jaco P. Dorenbos et al. · European Journal of Inorganic Chemistry · 1999 · 41 citations

Engineering, Molecular Biology, Chemistry +19

Target Immobilization as a Strategy for NMR-Based Fragment Screening: Comparison of TINS, STD, and SPR for Fragment Hit Identification

Masakazu Kobayashi, Kim Retra, Francis Figaroa et al. · SLAS DISCOVERY · 2010 · 40 citations · Full text

The new anticancer drug [(2R )-aminomethylpyrrolidine](1,1-cyclobutanedicarboxylato)platinum(II) and its toxic S enantiomer do interact differently with nucleic acids

Marieke J. Bloemink, Janice M. J. Pérez, Robert J. Heetebrij et al. · JBIC Journal of Biological Inorganic Chemistry · 1999 · 15 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Nucleic Acid Chemistry +10