Albert Stewart

Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations

Ted W. Johnson, Paul Richardson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 585 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

WaterLOGSY as a method for primary NMR screening: Practical aspects and range of applicability

Claudio Dalvit, Gianpaolo Fogliatto, Albert Stewart et al. · Journal of Biomolecular NMR · 2001 · 560 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +1

HGF/c-Met Acts as an Alternative Angiogenic Pathway in Sunitinib-Resistant Tumors

Farbod Shojaei, Joseph H. Lee, Brett H. Simmons et al. · Cancer Research · 2010 · 311 citations

Medicine, Oncology, Pharmacology +17

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes.

Stuart M. Arfin, R.L. Kendall, Laurence S. Hall et al. · Proceedings of the National Academy of Sciences · 1995 · 256 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation.

Neil Q. McDonald, Albert Stewart, Stephen Dowd et al. · Nature Structural Biology · 1999 · 148 citations

Life Sciences, Biochemistry, Molecular Biology +16