HGF/c-Met Acts as an Alternative Angiogenic Pathway in Sunitinib-Resistant Tumors

Farbod Shojaei, Joseph H. Lee, Brett H. Simmons, +7

Cancer Research

OncologyAngiogenesisEndothelial CellsMedicinePharmacology +13

Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies

Dana D. Hu‐Lowe, Enhong Chen, Lianglin Zhang, +22

Cancer Research

Action ComplementaryImmunologyTumor BiologyMatrigel AngiogenesisAngiogenesis +14

Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer

Farbod Shojaei, Nathan Scott, Xiaolin Kang, +8

Journal of Experimental & Clinical Cancer Research

Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia

Manoj Kumar Kashyap, Carlos I. Amaya-Chanaga, Deepak Kumar, +16

Journal of Hematology & Oncology

HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis

Farbod Shojaei, Brett H. Simmons, Joseph H. Lee, +2

Cancer Letters

Hgf/c-met PathwayOncologyMedicinePhotocarcinogenesisTumor Suppressor +6

A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies

Shu‐Hui Liu, Yin Gu, Bernadette Pascual, +25

Blood Advances

VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma

Bharat K. Majeti, Joseph H. Lee, Brett H. Simmons, +1

BMC Cancer

Comparison of dynamic contrast‐enhanced <scp>MR</scp>, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of <scp>PF</scp>‐03084014 and sunitinib

Cathy C. Zhang, Zhengming Yan, Anand Giddabasappa, +11

Cancer Medicine

Combination of a MEK inhibitor at sub-MTD with a PI3K/mTOR inhibitor significantly suppresses growth of lung adenocarcinoma tumors in KrasG12D-LSL mice

Brett H. Simmons, Joseph H. Lee, Kush Lalwani, +8

Cancer Chemotherapy and Pharmacology

MedicinePathologyBronchial NeoplasmCancer BiologyPi3k/mtor Inhibitor +9

Contrast agents for quantitative microCT of lung tumors in mice.

K. Lalwani, Anand Giddabasappa, Peter Olson, +6

PubMed

Contrast AgentsNanotherapeuticsEngineeringOncologic ImagingImaging Agent +21