Significance of filamin A in mTORC2 function in glioblastoma

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.1K citations

Molecular Biology, Tumor Biology, Signaling Pathway +16

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim et al. · Current Biology · 2004 · 2.6K citations · Full text

Protein Function, Signal Transduction, Raptor-independent Pathway +12

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Estela Jacinto, Robbie Loewith, Anja Schmidt et al. · Nature Cell Biology · 2004 · 2.1K citations

Signal Transduction, Natural Sciences, Cell Interaction +10

SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity

Estela Jacinto, Valeria Facchinetti, Dou Liu et al. · Cell · 2006 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Regulation +12

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

Anguraj Sadanandam, Costas A. Lyssiotis, Krisztián Homicskó et al. · Nature Medicine · 2013 · 954 citations · Full text

Tumor Biology, Oncology, Tumor Heterogeneity +9