Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition

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Participation of p53 protein in the cellular response to DNA damage.

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Histone H2AX Is Phosphorylated in an ATR-dependent Manner in Response to Replicational Stress

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Jaroslaw Dziegielewski et al. · Nature Cell Biology · 2005 · 646 citations

Genome Instability, Protein Kinase, Cell Cycle +4