Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming

Systemic Lupus Erythematosus

Anisur Rahman, David Isenberg · New England Journal of Medicine · 2008 · 1.6K citations

Life Sciences, Immunology, Nephrology +17

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5

Christopher D.C. Allen, K. Mark Ansel, Caroline M. R. Low et al. · Nature Immunology · 2004 · 774 citations

Life Sciences, Cell Biology, Molecular Biology +10

Diffuse proliferative lupus nephritis: Identification of specific pathologic features affecting renal outcome

Howard A. Austin, Larry R. Muenz, Kathleen Joyce et al. · Kidney International · 1984 · 722 citations

Medicine, Nephrology, Pathology +16

Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

Richard J. Riese, Paula Wolf, Dieter Brömme et al. · Immunity · 1996 · 529 citations · Full text

Life Sciences, Biochemistry, Immunology +16

Cathepsin S Required for Normal MHC Class II Peptide Loading and Germinal Center Development

Guo‐Ping Shi, Jóse A. Villadangos, Glenn Dranoff et al. · Immunity · 1999 · 522 citations · Full text

Life Sciences, Biochemistry, Immunology +14