Concepedia

N-Aryl-γ-lactams as integrin αvβ3 antagonists

Ning Xi, Stephen Arvedson, S.W.E. Eisenberg, Nianhe Han, Michael K. Handley, Liang Huang, Qi Huang, Alexander S. Kiselyov, Qingyian Liu, Yuelie Lu,

Bioorganic & Medicinal Chemistry Letters · 2004 · 24 citations · 11 references

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11

Crystal Structure of the Extracellular Segment of Integrin αVβ3

Jian-Ping Xiong, Thilo Stehle, Beate Diefenbach et al. · Science · 2001 · 1.3K citations · Full text

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Docking Studies on α<sub>v</sub>β<sub>3</sub> Integrin Ligands:  Pharmacophore Refinement and Implications for Drug Design

Luciana Marinelli, Antonio Lavecchia, Kay‐E. Gottschalk et al. · Journal of Medicinal Chemistry · 2003 · 121 citations · Full text

, , +17

Identification and in vivo efficacy of small-molecule antagonists of integrin αvβ3 (the vitronectin receptor)

William H. Miller, Richard M. Keenan, Robert N. Willette et al. · Drug Discovery Today · 2000 · 100 citations

, , +13

Biocatalytic approach to enantiomerically pure β-amino acids

Vadim A. Soloshonok, Nataly A. Fokina, A. V. RYBAKOVA et al. · Tetrahedron Asymmetry · 1995 · 92 citations

, , +14

Nonpeptide α<sub>v</sub>β<sub>3</sub> Antagonists. 1. Transformation of a Potent, Integrin-Selective α<sub>IIb</sub>β<sub>3</sub> Antagonist into a Potent α<sub>v</sub>β<sub>3</sub> Antagonist

Mark E. Duggan, Le T. Duong, John Fisher et al. · Journal of Medicinal Chemistry · 2000 · 88 citations · Full text

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