Nianhe Han

Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of <i>N</i>-Aryl Cinnamides

Elizabeth M. Doherty, Christopher Fotsch, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2004 · 103 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structure−Activity Relationships of a Series of Pyrrolo[3,2-<i>d</i>]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

Mark H. Norman, Ning Chen, Zhidong Chen et al. · Journal of Medicinal Chemistry · 2000 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

Dale L. Boger, Weiya Yun, Nianhe Han · Bioorganic & Medicinal Chemistry · 1995 · 62 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis, Chemical Properties, and Preliminary Evaluation of Substituted CBI Analogs of CC-1065 and the Duocarmycins Incorporating the 7-Cyano-1,2,9,9a-tetrahydrocyclopropa[<i>c</i>]benz[<i>e</i>]indol-4-one Alkylation Subunit:  Hammett Quantitation of the Magnitude of Electronic Effects on Functional Reactivity

Dale L. Boger, Nianhe Han, Christine M. Tarby et al. · The Journal of Organic Chemistry · 1996 · 53 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Engineering metal coordination sites into the antibody light chain

Warren S. Wade, Jong Sung Koh, Nianhe Han et al. · Journal of the American Chemical Society · 1993 · 45 citations

Pharmacy, Biomolecular Engineering, Chemistry +11