1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

GC base sequence recognition by oligoimidazolecarboxamide and C-terminus-modified analogs of distamycin deduced from circular dichroism, proton nuclear magnetic resonance, and methidiumpropylethylenediaminetetraacetate-iron(II) footprinting studies

Moses Lee, Andrea L. Rhodes, Michael D. Wyatt et al. · Biochemistry · 1993 · 403 citations

Pharmacy, Biochemistry, Molecular Biology +17

CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.

L. J. Haňka, A Dietz, S. A. Gerpheide et al. · The Journal of Antibiotics · 1978 · 272 citations · Full text

Life Sciences, Biotechnology, Microbiology +9

Reaction of the Antitumor Antibiotic CC-1065 with DNA: Structure of a DNA Adduct with DNA Sequence Specificity

Laurence H. Hurley, Vincent L. Reynolds, David H. Swenson et al. · Science · 1984 · 204 citations

Life Sciences, Molecular Biology, Pharmacology +17

Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity

Vincent L. Reynolds, Ian J. Molineux, David Kaplan et al. · Biochemistry · 1985 · 203 citations

Pharmacy, Molecular Biology, Chemotherapy +9

Duocarmycin A, a new antitumor antibiotic from Streptomyces.

ISAMI TAKAHASHI, Keiichi Takahashi, Michio Ichimura et al. · The Journal of Antibiotics · 1988 · 195 citations · Full text

Medicine, Microbiology, Chemotherapy +4