Weiya Yun

(+)- and ent-(-)-Duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA Alkylation Properties.Alkylation Site Models That Accommodate the Offset AT-Rich Adenine N3 Alkylation Selectivity of the Enantiomeric Agents

Dale L. Boger, Douglas S. Johnson, Weiya Yun · Journal of the American Chemical Society · 1994 · 118 citations

Pharmacy, Medicinal Chemistry, Bioorthogonal Chemistry +7

CBI-TMI: Synthesis and Evaluation of a Key Analog of the Duocarmycins. Validation of a Direct Relationship between Chemical Solvolytic Stability and Cytotoxic Potency and Confirmation of the Structural Features Responsible for the Distinguishing Behavior of Enantiomeric Pairs of Agents

Dale L. Boger, Weiya Yun · Journal of the American Chemical Society · 1994 · 79 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Molecular basis for sequence selective DNA alkylation by (+)- and ent-(−)-CC-1065 and related agents: Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity

Dale L. Boger, Douglas S. Johnson, Weiya Yun et al. · Bioorganic & Medicinal Chemistry · 1994 · 79 citations

Life Sciences, Molecular Biology, Dna Repair +9

Heck reaction on solid support: synthesis of indole analogs

Weiya Yun, Raju Mohan · Tetrahedron Letters · 1996 · 75 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

An improved synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI): a simplified analog of the CC-1065 alkylation subunit

Dale L. Boger, Weiya Yun, Bradley R. Teegarden · The Journal of Organic Chemistry · 1992 · 70 citations

Natural Sciences, Biochemistry, Chemistry +8