Concepedia

Retrosynthetic Analysis

Retrosynthetic Analysis is a systematic conceptual method in organic synthesis that belongs to the broader domain of synthetic planning, specifically characterized by the intellectual disconnection of a target molecule into progressively simpler precursor structures through the identification of strategic bond disconnections and functional group transformations, ultimately enabling the determination of viable synthetic routes.

77K

Publications

2.6M

Citations

129.9K

Authors

7.2K

Institutions

Publications per year

2017–2026

9K

Variants

Retrosynthesis

Parents

Children

Publications

77K

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

, , +11

An overview of N-heterocyclic carbenes

Matthew N. Hopkinson, Christian Richter, Michael Schedler et al. · Nature · 2014 · 4.2K citations

, , +10

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

Keary M. Engle, Tian‐Sheng Mei, Masayuki Wasa et al. · Accounts of Chemical Research · 2011 · 2.7K citations

, , +16

The isomers of silacyclopropane

Mark S. Gordon · Chemical Physics Letters · 1980 · 1.8K citations

, , +4

A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′)

E. J. Corey, P.L. Fuchs · Tetrahedron Letters · 1972 · 1.6K citations

, , +7

1–5 of 77K

Authors

129.9K

  1. AF
    Alois Fürstner

    Max-Planck-Institut für Kohlenforschung, Germany

    122 publications · 11.8K citations

    66

    h-index

  2. EJ
    E. J. Corey

    Harvard University, United States

    167 publications · 13.7K citations

    60

    h-index

  3. SJ
    Samuel J. Danishefsky

    Columbia University, United States

    178 publications · 10.4K citations

    60

    h-index

  4. KC
    K. C. Nicolaou

    Scripps Research Institute, United States

    133 publications · 9K citations

    58

    h-index

  5. BM
    Barry M. Trost

    Stanford University, United States

    122 publications · 7.5K citations

    54

    h-index

1–5 of 129.9K

Institutions

7.2K

  1. Scripps Research Institute

    San Diego, United States

    99 h-index

    1.8K publications

    160.8K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    96 h-index

    9.4K publications

    293.9K citations

  3. Chinese Academy of Sciences

    Beijing, China

    93 h-index

    5.1K publications

    189.4K citations

  4. Shanghai Institute of Organic Chemistry

    Shanghai, China

    88 h-index

    3K publications

    125.2K citations

  5. Kyoto University

    Kyoto, Japan

    78 h-index

    2.3K publications

    101.1K citations

  6. Harvard University

    Cambridge, United States

    77 h-index

    932 publications

    66.1K citations

  7. The University of Tokyo

    Tokyo, Japan

    72 h-index

    2.2K publications

    87.5K citations

  8. Max-Planck-Institut für Kohlenforschung

    Mülheim, Germany

    70 h-index

    619 publications

    46.7K citations

1–8 of 7.2K

Venues

  1. Journal of the American Chemical Society

    JACS · 3.6K publications · 241.1K citations

    181

    h-index

  2. Angewandte Chemie International Edition

    1.8K publications · 123.9K citations

    147

    h-index

  3. Tetrahedron

    8.6K publications · 287.7K citations

    146

    h-index

  4. Tetrahedron Letters

    17.2K publications · 485.2K citations

    126

    h-index

  5. The Journal of Organic Chemistry

    JOC · 5.8K publications · 210.8K citations

    116

    h-index

1–5