Mark E. Duggan

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

Craig W. Lindsley, Zhijian Zhao, William Leister et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 501 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models

Gene G. Kinney, Julie A. O’Brien, Wei Lemaire et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 299 citations

Life Sciences, Neuroscience, Pharmacology +17

Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

George D. Hartman, Melissa S. Egbertson, Wasyl Halczenko et al. · Journal of Medicinal Chemistry · 1992 · 297 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp

Melissa S. Egbertson, C. T.‐C. CHANG, Mark E. Duggan et al. · Journal of Medicinal Chemistry · 1994 · 178 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members

Deborah Defeo-Jones, Stanley F. Barnett, Sheng Fu et al. · Molecular Cancer Therapeutics · 2005 · 174 citations

Life Sciences, Oncology, Pharmacology +17