Tumor hypoxia, p53, and prognosis in cervical cancers

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber, Cynthia Osmanian, Tyler Jacks et al. · Nature · 1996 · 2.3K citations

Life Sciences, Cell Biology, Oncology +16

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

Michael Höckel, Karlheinz Schlenger, Bernard Aral et al. · PubMed · 1996 · 1.7K citations

Medicine, Gynecology, Oncology +13

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest

Vjekoslav Dulić, William K. Kaufmann, S J Wilson et al. · Cell · 1994 · 1.5K citations

Medicine, Cell Biology, Oncology +17

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

Cathy A. Finlay, Philip W. Hinds, Tse‐Hua Tan et al. · Molecular and Cellular Biology · 1988 · 1.1K citations · Full text

Medicine, Genetics, Molecular Biology +14

Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer

Alan Storey, Miranda Thomas, Ann Kalita et al. · Nature · 1998 · 983 citations

Medicine, Genetics, Oncology +14