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The Kelch Repeat Protein KLHDC10 Regulates Oxidative Stress-Induced ASK1 Activation by Suppressing PP5

Yusuke Sekine, Ryo Hatanaka, Takeshi Watanabe, N. Sono, Shun-ichiro Iemura, Tohru Natsume, Erina Kuranaga, Masayuki Miura, Kohsuke Takeda, Hidenori Ichijo

Molecular Cell · 2012 · 83 citations · 34 references

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34

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Andrea H. Brand, Norbert Perrimon · Development · 1993 · 9.8K citations

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Masao Saitoh · The EMBO Journal · 1998 · 2.4K citations · Full text

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Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie et al. · Science · 1997 · 2.3K citations

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ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

Kei Tobiume, Atsushi Matsuzawa, Takumi Takahashi et al. · EMBO Reports · 2001 · 1.2K citations · Full text

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity

Atsushi Matsuzawa, Kaoru Saegusa, Takuya Noguchi et al. · Nature Immunology · 2005 · 659 citations

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