Yusuke Sekine

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

M.S. Halliday, Helois Radford, Yusuke Sekine et al. · Cell Death and Disease · 2015 · 369 citations · Full text

Mutations in a translation initiation factor identify the target of a memory-enhancing compound

Yusuke Sekine, Alisa Zyryanova, Ana Crespillo-Casado et al. · Science · 2015 · 231 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +22

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

Alisa Zyryanova, Félix Weis, Alexandre Faille et al. · Science · 2018 · 221 citations · Full text

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

Kohsuke Takeda, Yoshiko Komuro, Teruyuki Hayakawa et al. · Proceedings of the National Academy of Sciences · 2009 · 146 citations · Full text

Phosphoglycerate Mutase, Pgam Family, Corresponding Drosophila +19

The DEAH-Box RNA Helicase DHX15 Activates NF-κB and MAPK Signaling Downstream of MAVS During Antiviral Responses

Kenta Mosallanejad, Yusuke Sekine, Seiko Ishikura-Kinoshita et al. · Science Signaling · 2014 · 93 citations