Concepedia

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

Kei Tobiume, Atsushi Matsuzawa, Takumi Takahashi, Hideki Nishitoh, Keiichi Morita, Kohsuke Takeda, Osamu Minowa, Kohei Miyazono, Tetsuo Noda, Hidenori Ichijo

EMBO Reports · 2001 · 1.2K citations · 21 references

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21

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

Zhengui Xia, Martin Dickens, Joël Raingeaud et al. · Science · 1995 · 5.3K citations

, , +16

Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Masao Saitoh · The EMBO Journal · 1998 · 2.4K citations · Full text

, , +13

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie et al. · Science · 1997 · 2.3K citations

, , +16

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

Marcel Verheij, Ron Bose, Xin Lin et al. · Nature · 1996 · 1.8K citations

, , +14

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Cathy Tournier, Patricia Hess, Derek Yang et al. · Science · 2000 · 1.7K citations

, , +17