Concepedia

Publication | Open Access

High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

DOIFull Paper Access

57

Citations

38

References

2013

Year

Albrecht Stenzinger, Volker Endris, Frederick Klauschen, Bruno V. Sinn, Katja Lorenz, Arne Warth, Benjamin Goeppert, Volker Ehemann, Alexander Muckenhuber, Carsten Kamphues,
BMC Cancer

Abstract

Sirt1 is an independent prognosticator in PDACs and plays an important role in pancreatic cancer cell growth, which can be levered out by small molecule inhibition. Our data warrant further studies on SIRT1 as a novel chemotherapeutic target in PDAC.

References

YearCitations

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