Concepedia

The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model

El Mustapha Bahassi, C. Gail Penner, Susan B. Robbins, Elisia D. Tichy, Estrella Feliciano, Moying Yin, Li Liang, Li Deng, Jay A. Tischfield, Peter J. Stambrook

Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2006 · 26 citations · 40 references

DOI

Concepts

References

40

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

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Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

Marijke Wasielewski, Deborah J. Thompson, Catherine Phelan et al. · Nature Genetics · 2002 · 1.1K citations

, , +11

The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Jacob Falck, Niels Mailand, Randi G. Syljuåsen et al. · Nature · 2001 · 1.1K citations

, , +12

A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations

Pentao Liu, Nancy A. Jenkins, Neal G. Copeland · Genome Research · 2003 · 1K citations · Full text

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Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members

Seong‐Tae Kim, Dae‐Sik Lim, Christine E. Canman et al. · Journal of Biological Chemistry · 1999 · 814 citations · Full text

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