Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

Deborah Ford, Douglas F. Easton, Michael R. Stratton et al. · The American Journal of Human Genetics · 1998 · 3K citations · Full text

Life Sciences, Genetics, Oncology +17

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

Satomi Matsuoka · 1998 · 1.3K citations

Life Sciences, Cell Biology, Molecular Biology +17

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

Sheau-Yann Shieh, Katsuyuki Tamai, Yoichi Taya et al. · Genes & Development · 2000 · 955 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Heterozygous Germ Line <i>hCHK2</i> Mutations in Li-Fraumeni Syndrome

Daphne W. Bell, Jennifer M. Varley, Tara E. Szydlo et al. · Science · 1999 · 902 citations

Life Sciences, Genetics, Molecular Genetics +17

Prevalence of BRCA1 and BRCA2 Gene Mutations in Patients With Early-Onset Breast Cancer

Julian Peto, Nadine Collins, Rita Barfoot et al. · JNCI Journal of the National Cancer Institute · 1999 · 879 citations

Medicine, Genetics, Oncology +12