Concepedia

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus

Anna Kanerva, Kurt R. Zinn, Tandra R. Chaudhuri, John Lam, Kaori Suzuki, Taco G. Uil, Tanja Hakkarainen, Gerd Bauerschmitz, Minghui Wang, Bin Liu,

Molecular Therapy · 2003 · 172 citations · 35 references

DOIFull text

Open access

Concepts

References

35

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Wadih Arap, Renata Pasqualini, Erkki Ruoslahti · Science · 1998 · 2.1K citations

, , +17

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

, , +14

A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

Fadlo R. Khuri, John Nemunaitis, Ian Ganly et al. · Nature Medicine · 2000 · 1.1K citations

, , +8

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

Carla Heise, Adam Sampson-Johannes, Angelica Williams et al. · Nature Medicine · 1997 · 947 citations

, , +13

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo

Juàn Fueyo, Candelaria Gomez‐Manzano, Ramón Alemany et al. · Oncogene · 2000 · 772 citations

, , +16