Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma Pathway

Juàn Fueyo, Ramón Alemany, Candelaria Gomez‐Manzano, +11

JNCI Journal of the National Cancer Institute

A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.

Kaori Suzuki, Juàn Fueyo, Victor Krasnykh, +3

PubMed

Oncolytic PotencyViral ReplicationSynthetic VirologyImmunologyReplicative Adenovirus +15

Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells

Jun Sunayama, Kenichiro Matsuda, Atsushi Satō, +8

Stem Cells

Glioblastoma Stem-like CellsCell ProliferationCancer BiologyGliomaTumor Biology +18

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus

Anna Kanerva, Kurt R. Zinn, Tandra R. Chaudhuri, +11

Molecular Therapy

Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism

Zhongshuang Hu, Taisuke Murakami, Kaori Suzuki, +4

PLoS ONE

Microbial PathogensLung InflammationApoptosisImmunologyImmune Regulation +22

MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis

Atsushi Satō, Jun Sunayama, Kenichiro Matsuda, +7

Stem Cells

Epidermal FABP (FABP5) Regulates Keratinocyte Differentiation by 13(S)-HODE-Mediated Activation of the NF-κB Signaling Pathway

Eisaku Ogawa, Yuji Owada, Shuntaro Ikawa, +10

Journal of Investigative Dermatology

Nf-κb Signaling PathwaySkin DevelopmentSignal TransductionSignaling PathwayCell Regulation +8

Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells

Jun Sunayama, Atsushi Satō, Kenichiro Matsuda, +8

Neuro-Oncology

Glioblastoma Stem-like CellsMtor Inhibitor RapamycinHigh-grade GliomasCancer BiologyGlioma +18

Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells

Kaori Suzuki, Taisuke Murakami, Kyoko Kuwahara‐Arai, +3

International Immunology

InflammationSevere Sepsis/endotoxin ShockSevere SepsisEndothelial CellsMicrobial Pathogens +13

Expression and Function of Receptors for Advanced Glycation End Products in Bovine Corneal Endothelial Cells

Yuichi Kaji, Shiro Amano, Tomohiko Usui, +8

Investigative Ophthalmology & Visual Science