Concepedia

Replication-competent Vectors

Replication-Competent Vectors is a type of viral vector vaccine that retains the ability to replicate within host cells, enabling sustained antigen expression and enhanced immune response induction, distinguishing it from replication-deficient vectors by its preserved capacity for autonomous viral replication.

405

Publications

32.8K

Citations

2.5K

Authors

568

Institutions

Publications per year

2017–2026

50

Variants

Replication-competent Viral Vectors

Parents

Publications

405

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

, , +14

Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

Romain Zufferey, Thomas J. Dull, Ronald J. Mandel et al. · Journal of Virology · 1998 · 1.8K citations · Full text

, , +17

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

A. Dusty Miller, Carol Buttimore · Molecular and Cellular Biology · 1986 · 1.3K citations

, , +15

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine

Jerald Sadoff, Mathieu Le Gars, Georgi Shukarev et al. · New England Journal of Medicine · 2021 · 1.2K citations · Full text

, , +16

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

Ana María Henao-Restrepo, Anton Camacho, Ira M. Longini et al. · The Lancet · 2016 · 1.1K citations · Full text

, , +17

1–5 of 405

Authors

2.5K

  1. ME
    Mariano Estéban

    Centro Nacional de Biotecnología, Spain

    10 publications · 512 citations

    10

    h-index

  2. MR
    Marjorie Robert-Guroff

    National Cancer Institute, United States

    9 publications · 386 citations

    9

    h-index

  3. NK
    Noriyuki Kasahara

    University of California, Los Angeles, United States

    8 publications · 465 citations

    8

    h-index

  4. GP
    Giuseppe Pantaleo

    University of Lausanne, Switzerland

    7 publications · 245 citations

    7

    h-index

  5. BL
    Bertram L. Jacobs

    Arizona State University, United States

    7 publications · 245 citations

    7

    h-index

1–5 of 2.5K

Institutions

568

  1. National Institutes of Health

    Bethesda, United States

    21 h-index

    122 publications

    17.2K citations

  2. National Cancer Institute

    Bethesda, United States

    19 h-index

    93 publications

    3.6K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    15 h-index

    81 publications

    10.1K citations

  4. University of Alabama at Birmingham

    Birmingham, United States

    14 h-index

    43 publications

    3.1K citations

  5. University of Washington

    Seattle, United States

    11 h-index

    24 publications

    1.1K citations

  6. Fred Hutch Cancer Center

    Seattle, United States

    11 h-index

    30 publications

    5.5K citations

  7. Duke Medical Center

    Durham, United States

    11 h-index

    39 publications

    1.8K citations

  8. Harvard University

    Cambridge, United States

    11 h-index

    50 publications

    4.3K citations

1–8 of 568

Venues

  1. Journal of Virology

    JVI · 90 publications · 9K citations

    47

    h-index

  2. Human Gene Therapy

    31 publications · 2.6K citations

    26

    h-index

  3. PubMed

    Repository · 31 publications · 1.3K citations

    21

    h-index

  4. Molecular Therapy

    22 publications · 1.5K citations

    19

    h-index

  5. PLoS ONE

    20 publications · 697 citations

    16

    h-index

1–5