Concepedia

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot, Daan J.A. Crommelin, C. Russell Middaugh, Gerhard Winter

Journal of Pharmaceutical Sciences · 2009 · 203 citations · 23 references

DOI

Concepts

References

23

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 588 citations · Full text

, , +16

Laser light scattering in biochemistry

Wyn Brown · Journal of Biochemical and Biophysical Methods · 1992 · 242 citations

, , +10

Quantitation of Aggregate Levels in a Recombinant Humanized Monoclonal Antibody Formulation by Size-Exclusion Chromatography, Asymmetrical Flow Field Flow Fractionation, and Sedimentation Velocity

John P. Gabrielson, Mark L. Brader, Allen H. Pekar et al. · Journal of Pharmaceutical Sciences · 2006 · 174 citations

, , +17

Immunogenicity of aggregates of recombinant human growth hormone in mouse models

Amber Haynes Fradkin, John F. Carpenter, Theodore W. Randolph · Journal of Pharmaceutical Sciences · 2009 · 169 citations · Full text

, , +10

Laser light scattering in biochemistry

Stephen E. Harding, D. B. Sattelle, Victor A. Bloomfield · Medical Entomology and Zoology · 1992 · 165 citations

, , +10