Concepedia

Macromolecular Purity Analysis

Macromolecular Purity Analysis is a methodological framework within analytical biochemistry that employs size-exclusion chromatography to assess the homogeneity of macromolecular preparations by resolving and quantifying high-molecular-weight species based on their hydrodynamic volume, thereby differentiating target macromolecules from aggregates, fragments, and contaminating biomolecules.

101

Publications

8.9K

Citations

318

Authors

85

Institutions

Publications per year

2017–2026

5

Parents

Publications

101

Estimation of the molecular weights of proteins by Sephadex gel-filtration

P Andrews · Biochemical Journal · 1964 · 3.9K citations · Full text

, , +12

Ultracentrifuge Studies with Absorption Optics. IV. Molecular Weight Determinations at the Microgram Level<sup>*</sup>

H. K. Schachman, Stuart J. Edelstein · Biochemistry · 1966 · 318 citations

, , +8

The Specific Refractive Increment of Some Purified Proteins

Gertrude E. Perlmann, L. G. Longsworth · Journal of the American Chemical Society · 1948 · 281 citations

, , +7

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2009 · 203 citations

, , +17

Purification of gram quantities of C60. A new inexpensive and facile method

Walter A. Scrivens, Peter V. Bedworth, James M. Tour · Journal of the American Chemical Society · 1992 · 183 citations

, , +7

1–5 of 101

Authors

318

  1. TY
    T. Yagi

    Kōchi University, Japan

    1 publications · 31 citations

    1

    h-index

  2. OG
    Owen G. Davies

    Loughborough University, United Kingdom

    1 publications · 19 citations

    1

    h-index

  3. AG
    Anton G. Enenkel

    University of Alberta, Canada

    1 publications · 14 citations

    1

    h-index

  4. DP
    Daniela Parisi

    University of Pisa, Italy

    1 publications · 30 citations

    1

    h-index

  5. EM
    E. M. Press

    University of Oxford, United Kingdom

    1 publications · 23 citations

    1

    h-index

1–5 of 318

Institutions

85

  1. Pfizer (United States)

    New York, United States

    2 h-index

    9 publications

    393 citations

  2. Loughborough University

    Loughborough, United Kingdom

    1 h-index

    6 publications

    114 citations

  3. Fuchu Hospital

    Izumi, Japan

    1 h-index

    4 publications

    108 citations

  4. Ministry of Public Health

    Nonthaburi, Thailand

    1 h-index

    1 publications

    12 citations

  5. Uppsala University

    Uppsala, Sweden

    1 h-index

    1 publications

    22 citations

  6. National Metrology Institute of South Africa

    Pretoria, South Africa

    1 h-index

    3 publications

    36 citations

  7. University of Alabama

    Tuscaloosa, United States

    1 h-index

    2 publications

    32 citations

  8. University of Belgrade

    Belgrade, Serbia

    1 h-index

    5 publications

    510 citations

1–8 of 85

Venues

  1. Biochemistry

    22 publications · 1.6K citations

    18

    h-index

  2. Macromolecules

    9 publications · 276 citations

    9

    h-index

  3. Journal of the American Chemical Society

    JACS · 6 publications · 565 citations

    6

    h-index

  4. Analytical Chemistry

    4 publications · 157 citations

    4

    h-index

  5. Biochemical Journal

    3 publications · 217 citations

    3

    h-index

1–5