Concepedia

RPR 107393, a Potent Squalene Synthase Inhibitor and Orally Effective Cholesterol-Lowering Agent: Comparison with Inhibitors of HMG-CoA Reductase

Dilip Amin, Ruth Z. Rutledge, Saul Needle, Helen Galczenski, Kent Neuenschwander, Anthony C. Scotese, Martin P. Maguire, Raymond C. Bush, Glenda E. Bilder, Mark H. Perrone

Journal of Pharmacology and Experimental Therapeutics · 1997 · 68 citations · 21 references

DOI

Concepts

References

21

The Lipid Research Clinics Coronary Primary Prevention Trial Results

JAMA · 1984 · 2.8K citations

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Manual of pharmacologic calculations with computer programs

International Journal of Biochemistry · 1988 · 1.5K citations

, , +12

Lovastatin decreases coenzyme Q levels in humans.

Karl Folkers, Peter H. Langsjoen, Richard A. Willis et al. · Proceedings of the National Academy of Sciences · 1990 · 427 citations

, , +16

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

Yoshio Tsujita, Masao Kuroda, Yoko Shimada et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1986 · 375 citations

, , +14

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

James D. Bergstrom, Marc M. Kurtz, Deborah J. Rew et al. · Proceedings of the National Academy of Sciences · 1993 · 335 citations

, , +12