ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

Akira Endo, Masao Kuroda, Yoshio Tsujita

The Journal of Antibiotics

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

Yoshio Tsujita, Masao Kuroda, Yoko Shimada, +8

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

OxysterolBiochemistryMedicineLipoprotein MetabolismHypolipidemic Effect +7

Inhibition of Cholesterol Synthesis <i>in vitro</i> and <i>in vivo</i> by ML‐236A and ML‐236B, Competitive Inhibitors of 3‐Hydroxy‐3‐methylglutaryl‐Coenzyme A Reductase

Akira Endo, Yoshio Tsujita, Masao Kuroda, +1

European Journal of Biochemistry

OxysterolPharmacological StudyBiochemistryLiver SlicesMedicine +13

WHHL‐Rabbit: a low density lipoprotein receptor‐deficient animal model for familial hypercholesterolemia

Kazuhiko Tanzawa, Yoko Shimada, Masao Kuroda, +3

FEBS Letters

Metabolic SyndromeFamilial HypercholesterolemiaLipid DisorderCardiovascular DiseaseInherited Metabolic Disease +8

Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

Teiichiro Koga, Yohko Shimada, Masao Kuroda, +3

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Tissue-selective InhibitionPravastatin SodiumOxysterolBiochemistryMedicine +6

Reduction of Serum Cholesterol Levels Alters Lesional Composition of Atherosclerotic Plaques

Masashi Shiomi, Takashi Ito, Toyohiro Tsukada, +7

Arteriosclerosis Thrombosis and Vascular Biology

Vascular DiseasePathologySerum Cholesterol ReductionHyperlipidemiaOxidative Stress +15

Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase

Yoshio Tsujita, Masao Kuroda, Kazuhiko Tanzawa, +2

Atherosclerosis

Animal PhysiologyOxysterol3-Hydroxy-3-methylglutaryl CoenzymeBiochemistryMedicine +10

The mechanism of lack of hypocholesterolemic effects of pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rats

Tomoyuki Fujioka, Futoshi Nara, Yoshio Tsujita, +3

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Hypocholesterolemic EffectsMetabolic SyndromePravastatin SodiumOxysterolBiochemistry +11

Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)

Nobufusa Serizawa, Keiko Nakagawa, KIYOSHI HAMANO, +3

The Journal of Antibiotics

BiotransformationBiochemistryMicrobial PhysiologyMicrobiologyMicrobial Hydroxylation

Mechanism for elevation of hepatic cholesterol synthesis and serum cholesterol levels in triton WR-1339-induced hyperlipidemia

Masao Kuroda, Kazuhiko Tanzawa, Yoshio Tsujita, +1

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Metabolic SyndromeTriton Wr-1339-induced HyperlipidemiaHepatologyBiochemistryMedicine +11