Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy

Carl Friddle, Teiichiro Koga, Edward M. Rubin, +1

Proceedings of the National Academy of Sciences

Cardiac MuscleHeart FailureLeft Ventricular RnaGeneticsGene Expression Profiling +15

A study to survey susceptible genetic factors responsible for troglitazone‐associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus

Ichiro Watanabe, Aiko Tomita, Miho Shimizu, +11

Clinical Pharmacology & Therapeutics

Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

Teiichiro Koga, Yohko Shimada, Masao Kuroda, +3

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Tissue-selective InhibitionPravastatin SodiumOxysterolBiochemistryMedicine +6

Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture

Toru Komai, Eiji Shigehara, Taro Tokui, +4

Biochemical Pharmacology

HepatologyMedicineLiver PhysiologyHepatotoxicityMetabolism +4

Epi-cochlioquinone A, a Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor Produced by Stachybotrys bisbyi.

Tomoyuki Fujioka, Keiko Yao, KIYOSHI HAMANO, +7

The Journal of Antibiotics

Pdx1 Expression in Irs2-deficient Mouse β-Cells Is Regulated in a Strain-dependent Manner

Ryo Suzuki, Kazuyuki Tobe, Yasuo Terauchi, +16

Journal of Biological Chemistry

Importance of acyl-coenzyme A:cholesterol acyltransferase 1/2 dual inhibition for anti-atherosclerotic potency of pactimibe

Ken Kitayama, Tatsuo Tanimoto, Teiichiro Koga, +3

European Journal of Pharmacology

Anti-atherosclerotic PotencyOxysterolBiochemistryDual InhibitionMedicine +9

Biological Activities of Novel Zaragozic Acids, the Potent Inhibitors of Squalene Synthase, Produced by the Fungus, Mollisia sp. SANK 10294.

Tatsuo Tanimoto, KIYOSHI HAMANO, Kaori Onodera, +6

The Journal of Antibiotics

Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-CoA:cholesterol acyltransferase inhibition in WHHL rabbits

Ken Kitayama, Teiichiro Koga, Naoyuki Maeda, +2

European Journal of Pharmacology

InflammationVascular DiseaseBiochemistryCardiovascular DiseaseAtherosclerosis +10

Tissue‐selective inhibition of sterol synthesis in mice by pravastatin sodium after a single or repeated oral administrations

Teiichiro Koga, Takashi Kikuchi, Atsuhiro Miyazaki, +1

Lipids

Liver SlicesPharmacotherapyExperimental PharmacologyMolecular PharmacologySterol Fraction +19