Concepedia

Deborah J. Rew

DJ

8

Publications

605

Citations

8

H-Index

1992

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Deborah J. Rew is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in biochemistry, natural sciences, and pharmacology.

Top concepts

BiochemistryNatural SciencesPharmacologyChemical BiologyMedicineOrganic ChemistryMedicinal ChemistryBiocatalysisBiosynthesisDrug Discovery

Publications per year

1992–1998

8

Publications

8

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

James D. Bergstrom, Marc M. Kurtz, Deborah J. Rew et al. · Proceedings of the National Academy of Sciences · 1993 · 334 citations · Full text

Biosynthesis, Natural Product Synthesis, Biochemistry +9

Zaragozic Acids D and D<sub>2</sub>: Potent Inhibitors of Squalene Synthase and of Ras Farnesyl-Protein Transferase

Claude Dufresne, Kenneth E. Wilson, Sheo B. Singh et al. · Journal of Natural Products · 1993 · 60 citations · Full text

Pharmaceutical Science, Altmetric Attention Score, Organic Chemistry +18

The isolation and structure elucidation of zaragozic acid C, a novel potent squalene synthase inhibitor.

Claude Dufresne, Kenneth E. Wilson, Deborah L. Zink et al. · Tetrahedron · 1992 · 58 citations

Medicinal Chemistry, Biochemistry, Zaragozic Acid C +9

Hepatic responses to inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase: a comparison of atorvastatin and simvastatin

James D. Bergstrom, Richard G. Bostedor, Deborah J. Rew et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1998 · 46 citations

Hepatic Responses, Hepatology, Biochemistry +12

Antimicrobial Activity of Viridiofungins.

Janet C. Onishi, James A. Milligan, Ángela Basilio et al. · The Journal of Antibiotics · 1997 · 39 citations · Full text

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