In vitro affinity maturation of human GM-CSF antibodies by targeted CDR-diversification

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

Bertrand Friguet, Alain Chaffotte, Lisa Djavadi‐Ohaniance et al. · Journal of Immunological Methods · 1985 · 1.2K citations

Biochemistry, Bioanalysis, Immunology +9

Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin

Toshio Kitamura, Tsuyoshi Tange, Takashi Terasawa et al. · Journal of Cellular Physiology · 1989 · 822 citations

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides 1 1Edited by I. A. Wilson

Achim Knappik, Liming Ge, Annemarie Honegger et al. · Journal of Molecular Biology · 2000 · 731 citations

Immunocytochemical Technique, Engineering, Modular Consensus Frameworks +12

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

Angel F. López, Dominic J. Williamson, Jennifer R. Gamble et al. · Journal of Clinical Investigation · 1986 · 715 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +18

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

David P. Gearing, Julie A. King, N M Gough et al. · The EMBO Journal · 1989 · 699 citations · Full text

Inflammation, Macrophage Biology, Cytokine +9