Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor

Creation of human tumour cells with defined genetic elements

William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations

Medicine, Cancer Biology, Genetics +13

Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

Takehiko Kamijo, Frédérique Zindy, Martine F. Roussel et al. · Cell · 1997 · 1.6K citations · Full text

Medicine, Genetics, Molecular Genetics +16

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

Simona Parrinello, Enrique Samper, Ana Krtolica et al. · Nature Cell Biology · 2003 · 1.1K citations · Full text

Education, Biochemistry, Cell Biology +13

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

Miguel Quintanilla, Ken Brown, Martin Ramsden et al. · Nature · 1986 · 865 citations

Medicine, Genetics, Molecular Genetics +12

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

Darren J. Baker, Karthik B. Jeganathan, J. Douglas Cameron et al. · Nature Genetics · 2004 · 726 citations

Veterinary Medicine, Genetics, Molecular Genetics +12