Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.5K citations

Life Sciences, Immunology, Pathology +17

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Weihong Liu, Amy Putnam, Gregory L. Szot et al. · The Journal of Experimental Medicine · 2006 · 2.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh et al. · Immunity · 2009 · 2.3K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Jason D. Fontenot, Jeffrey P. Rasmussen, Luke M. Williams et al. · Immunity · 2005 · 2.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14