Tobias Alexander

γ-secretase directly sheds the survival receptor BCMA from plasma cells

Sarah Laurent, Franziska Hoffmann, Peer‐Hendrik Kuhn et al. · Nature Communications · 2015 · 353 citations · Full text

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

Tobias Alexander, Ramona Sarfert, Jens Klotsche et al. · Annals of the Rheumatic Diseases · 2015 · 352 citations · Full text

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

Caroline von Spee-Mayer, Elise Siegert, Dimas Abdirama et al. · Annals of the Rheumatic Diseases · 2015 · 325 citations

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

Tobias Alexander, Andreas Thiel, Oliver Rosen et al. · Blood · 2008 · 307 citations · Full text

Human Chorionic Gonadotropin Attracts Regulatory T Cells into the Fetal-Maternal Interface during Early Human Pregnancy

Anne Schumacher, Nadja Brachwitz, Sindy Sohr et al. · The Journal of Immunology · 2009 · 301 citations