Tobias Alexander

γ-secretase directly sheds the survival receptor BCMA from plasma cells

Sarah Laurent, Franziska Hoffmann, Peer‐Hendrik Kuhn et al. · Nature Communications · 2015 · 364 citations · Full text

Life Sciences, Immunology, Pathobiology +13

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

Tobias Alexander, Ramona Sarfert, Jens Klotsche et al. · Annals of the Rheumatic Diseases · 2015 · 363 citations · Full text

Life Sciences, Immunology, Pharmacology +15

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

Caroline von Spee-Mayer, Elise Siegert, Dimas Abdirama et al. · Annals of the Rheumatic Diseases · 2015 · 340 citations

Life Sciences, Cell Biology, Immunology +17

Targeting CD38 with Daratumumab in Refractory Systemic Lupus Erythematosus

Lennard Ostendorf, Marie E. Burns, Pawel Durek et al. · New England Journal of Medicine · 2020 · 317 citations

Life Sciences, Immunology, Pharmacotherapy +17

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

Tobias Alexander, Andreas Thiel, Oliver Rosen et al. · Blood · 2008 · 310 citations · Full text

Life Sciences, Hematology, Immunology +17