Concepedia

Structure of an Hsp90-Cdc37-Cdk4 Complex

Cara K. Vaughan, U. Gohlke, Frank Sobott, Valerie M. Good, Maruf M. U. Ali, Chrisostomos Prodromou, Carol V. Robinson, Helen R. Saibil, Laurence H. Pearl

Molecular Cell · 2006 · 295 citations · 55 references

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55

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Paul Wan, Mathew J. Garnett, S. Mark Roe et al. · Cell · 2004 · 2.8K citations · Full text

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Accurate determination of local defocus and specimen tilt in electron microscopy

Joseph A. Mindell, Nikolaus Grigorieff · Journal of Structural Biology · 2003 · 1.4K citations

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Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

C. Erec Stebbins, Alicia A. Russo, Christine Schneider et al. · Cell · 1997 · 1.4K citations · Full text

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Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

Chrisostomos Prodromou, S. Mark Roe, Ronan O’Brien et al. · Cell · 1997 · 1.3K citations · Full text

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Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. Mark Roe, Chrisostomos Prodromou, Ronan O’Brien et al. · Journal of Medicinal Chemistry · 1999 · 999 citations · Full text

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