Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

Medicine, Molecular Genetics, Oncology +12

Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways

Hiroshi Aoki, Yasunari Takada, Seiji Kondo et al. · Molecular Pharmacology · 2007 · 525 citations

Life Sciences, Oncology, Pharmacology +17

Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP‐1 and NFκB transcription factors

Krishnan M. Dhandapani, Virendra B. Mahesh, Darrell W. Brann · Journal of Neurochemistry · 2007 · 297 citations

Medicine, Oncology, Pharmacology +17

Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

A. V. Knizhnik, Wynand P. Roos, Teodora Nikolova et al. · PLoS ONE · 2013 · 272 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.

Yuichi Hirose, Mitchel S. Berger, Russell O. Pieper · PubMed · 2001 · 236 citations

Medicine, Cancer Biology, Oncology +17