Wynand P. Roos

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

Wynand P. Roos, Luís F.Z. Batista, Steffen C. Naumann et al. · Oncogene · 2006 · 493 citations

Neuro-oncology, Malignant Disease, Oncogenic Agent +9

O⁶‐methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

Mirjam Hermisson, Andrea Klumpp, Wolfgang Wick et al. · Journal of Neurochemistry · 2006 · 311 citations · Full text

Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage

A. V. Knizhnik, Wynand P. Roos, Teodora Nikolova et al. · PLoS ONE · 2013 · 266 citations · Full text

Mitophagy, Methylating Agent Temozolomide, Apoptosis +18

Artesunate Derived from Traditional Chinese Medicine Induces DNA Damage and Repair

Paul C. H. Li, Elena Lam, Wynand P. Roos et al. · Cancer Research · 2008 · 204 citations · Full text

Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR–CHK1, p21, and NF-κB

Dorthe Aasland, Laura Götzinger, Laura Hauck et al. · Cancer Research · 2018 · 183 citations