Concepedia

Temozolomide Therapy

Temozolomide Therapy is a chemotherapeutic regimen that involves the systemic administration of temozolomide, a DNA-alkylating agent, to selectively induce tumor cell death in high-grade gliomas through methylation of guanine residues at the O6 position.

3.3K

Publications

260K

Citations

19.1K

Authors

3.6K

Institutions

Publications per year

2017–2026

1.3K

Parents

Publications

3.3K

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21.6K citations · Full text

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason et al. · The Lancet Oncology · 2009 · 7.8K citations

, , +17

<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma

Monika E. Hegi, Annie‐Claire Diserens, Thierry Gorlia et al. · New England Journal of Medicine · 2005 · 7.3K citations · Full text

, , +17

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

Mark R. Gilbert, James J. Dignam, Terri S. Armstrong et al. · New England Journal of Medicine · 2014 · 2.8K citations · Full text

, , +17

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

Roger Stupp, Sophie Taillibert, Andrew A. Kanner et al. · JAMA · 2017 · 2.6K citations · Full text

, , +16

1–5 of 3.3K

Authors

19.1K

  1. MW
    Michael Weller

    University Hospital of Zurich, Switzerland

    79 publications · 54.7K citations

    50

    h-index

  2. WW
    Wolfgang Wick

    Heidelberg University, Germany

    61 publications · 14.4K citations

    43

    h-index

  3. RS
    Roger Stupp

    University of Lausanne, Switzerland

    57 publications · 52.9K citations

    40

    h-index

  4. AA
    Alba A. Brandes

    Istituti di Ricovero e Cura a Carattere Scientifico, Italy

    58 publications · 43.1K citations

    39

    h-index

  5. MJ
    Martin J. van den Bent

    Erasmus MC Cancer Institute, Netherlands

    54 publications · 36.3K citations

    36

    h-index

1–5 of 19.1K

Institutions

3.6K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    55 h-index

    546 publications

    79.3K citations

  2. Neurological Surgery

    Rockville Centre, United States

    55 h-index

    452 publications

    59.3K citations

  3. University of California, San Francisco

    San Francisco, United States

    51 h-index

    426 publications

    72.8K citations

  4. Heidelberg University

    Heidelberg, Germany

    50 h-index

    493 publications

    78.4K citations

  5. Inserm

    Paris, France

    46 h-index

    440 publications

    63.4K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    44 h-index

    399 publications

    32.6K citations

  7. Mayo Clinic

    Rochester, United States

    43 h-index

    350 publications

    34.7K citations

  8. Sorbonne Université

    Paris, France

    42 h-index

    362 publications

    58.5K citations

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Venues

  1. Journal of Clinical Oncology

    181 publications · 25K citations

    77

    h-index

  2. Neuro-Oncology

    156 publications · 13.6K citations

    75

    h-index

  3. Clinical Cancer Research

    90 publications · 12.6K citations

    63

    h-index

  4. Journal of Neuro-Oncology

    216 publications · 11.4K citations

    61

    h-index

  5. PubMed

    Repository · 127 publications · 7.6K citations

    47

    h-index

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