Enzymatic Characterisation of USP7 Deubiquitinating activity and Inhibition

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Wen Xue, Lars Zender, Cornelius Miething et al. · Nature · 2007 · 2.4K citations · Full text

Tumour Clearance, Hepatology, Hepatocellular Carcinoma +13

A Dynamic Role of HAUSP in the p53-Mdm2 Pathway

Muyang Li, Christopher Brooks, Ning Kon et al. · Molecular Cell · 2004 · 664 citations · Full text

Autophagy, P53-mdm2 Pathway, Tumor Suppressor +4

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

Min Sup Song, Leonardo Salmena, Arkaitz Carracedo et al. · Nature · 2008 · 537 citations

Signal Transduction, Cell Signaling, Signal Recognition +4

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

Roger D. Everett · The EMBO Journal · 1997 · 496 citations · Full text

Herpesvirus Regulatory Protein, Viral Replication, Protein Function +8

Approval Summary for Bortezomib for Injection in the Treatment of Multiple Myeloma

Peter Bross, Robert C. Kane, Ann T. Farrell et al. · Clinical Cancer Research · 2004 · 336 citations · Full text