Ferroptosis as a p53-mediated activity during tumour suppression

Le Jiang, Ning Kon, Tongyuan Li, +5

Nature

Cancer ResearchMedicinePathologyCell DeathTumour Suppression +7

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

Tongyuan Li, Ning Kon, Le Jiang, +5

Cell

Tumor BiologyP53-mediated Cell-cycle ArrestOncologyMedicineTumor Suppression +9

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

Bo Chu, Ning Kon, Delin Chen, +6

Nature Cell Biology

Cancer ResearchDistinct Ferroptosis PathwayP53-mediated Tumour SuppressionMedicinePathology +7

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

Li Qiang, Liheng Wang, Ning Kon, +8

Cell

Metabolic SyndromeTranscriptional RegulationSignal TransductionPhysiologyGene Expression +11

A Dynamic Role of HAUSP in the p53-Mdm2 Pathway

Muyang Li, Christopher Brooks, Ning Kon, +1

Molecular Cell

AutophagyP53-mdm2 PathwayTumor SuppressorMedicineCell Biology +2

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

Alexander S. Banks, Ning Kon, Colette M. Knight, +5

Cell Metabolism

Prevents DiabetesMetabolic SyndromeInsulin SignalingSignal TransductionDiabetes +9

ARF-BP1/Mule Is a Critical Mediator of the ARF Tumor Suppressor

Delin Chen, Ning Kon, Muyang Li, +3

Cell

Signaling PathwayMedicineImmunologyArf Tumor SuppressorTumor Suppressor +5

iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4

Delin Chen, Bo Chu, Xin Yang, +7

Nature Communications

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma

Omid Tavana, Dawei Li, Chao Dai, +8

Nature Medicine

Neuro-oncologyPathologyNeural Stem CellHausp DeubiquitinatesNeuropathology +3

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode

Donglai Wang, Ning Kon, Gorka Lasso, +6

Nature

Transcriptional RegulationSignal TransductionWidespread Regulatory ModeMolecular PathwayCell Regulation +7