ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

Bo Chu, Ning Kon, Delin Chen, +6

Nature Cell Biology

Cancer ResearchDistinct Ferroptosis PathwayP53-mediated Tumour SuppressionMedicinePathology +7

Activation of <i>SAT1</i> engages polyamine metabolism with p53-mediated ferroptotic responses

Yang Ou, Shang-Jui Wang, Dawei Li, +2

Proceedings of the National Academy of Sciences

iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4

Delin Chen, Bo Chu, Xin Yang, +7

Nature Communications

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

Delin Chen, Omid Tavana, Bo Chu, +4

Molecular Cell

Cancer ResearchRadiation OncologyP53-independent Tumor SuppressionMedicineTumor Suppressor +6

Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis

Weiwei Cui, Dong Liu, Wei Gu, +1

Cell Death and Differentiation

Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition

Weiwei Cui, Meng Guo, Dong Liu, +20

Nature Cell Biology

DysbiosisGut MicrobiologyColorectal CancerPathologyFerroptosis Inhibition +7

Tryptophan Metabolism Acts as a New Anti‐Ferroptotic Pathway to Mediate Tumor Growth

Dong Liu, Chunhui Liang, Bin Huang, +13

Advanced Science

ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease

Shujuan Song, Zhenyi Su, Ning Kon, +6

Genes & Development

Structural insights into FSP1 catalysis and ferroptosis inhibition

Yun Lv, Chunhui Liang, Qichao Sun, +8

Nature Communications

Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis

Bin Huang, Hui Wang, Shuo Liu, +8

Nature Communications