Concepedia

Development of selective DprE1 inhibitors: Design, synthesis, crystal structure and antitubercular activity of benzothiazolylpyrimidine-5-carboxamides

Rupesh V. Chikhale, Sunil Menghani, Ramavath Babu, Ratnadeep Bansode, G. Bhargavi, Nazira Karodia, M.V. Rajasekharan, Anant Paradkar, Pramod Khedekar

European Journal of Medicinal Chemistry · 2015 · 108 citations · 31 references

DOI

Concepts

References

31

Benzothiazinones Kill <i>Mycobacterium tuberculosis</i> by Blocking Arabinan Synthesis

Vadim Makarov, Giulia Manina, Katarı́na Mikušová et al. · Science · 2009 · 727 citations · Full text

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n–3 Fatty Acids in Patients with Multiple Cardiovascular Risk Factors

New England Journal of Medicine · 2013 · 509 citations

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Towards a new combination therapy for tuberculosis with next generation benzothiazinones

Vadim Makarov, Benoît Lechartier, Ming Zhang et al. · EMBO Molecular Medicine · 2014 · 385 citations · Full text

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Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis

Ramesh Jayaram, Sheshagiri Gaonkar, Parvinder Kaur et al. · Antimicrobial Agents and Chemotherapy · 2003 · 338 citations · Full text

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High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

Thierry Christophe, Mary Jackson, Hee Kyoung Jeon et al. · PLoS Pathogens · 2009 · 329 citations · Full text

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