Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis

Ramesh Jayaram, Sheshagiri Gaonkar, Parvinder Kaur, +7

Antimicrobial Agents and Chemotherapy

Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes

Parvinder Kaur, Michael Aschner, Tore Syversen

NeuroToxicology

MedicineToxicologyNeuroprotectionNeurosciencePrimary Cell Cultures +3

Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against <i>Mycobacterium tuberculosis</i> : Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacy

Radha Krishan Shandil, Ramesh Jayaram, Parvinder Kaur, +7

Antimicrobial Agents and Chemotherapy

Isoniazid Pharmacokinetics-Pharmacodynamics in an Aerosol Infection Model of Tuberculosis

Ramesh Jayaram, Radha Krishan Shandil, Sheshagiri Gaonkar, +7

Antimicrobial Agents and Chemotherapy

Tuberculosis PreventionAntimicrobial ChemotherapyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic Modeling +16

Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious <i>in Vivo</i>

Pravin S. Shirude, Radha Krishan Shandil, C Sadler, +36

Journal of Medicinal Chemistry

PharmacotherapyAntimicrobial ChemotherapyPharmaceutical ChemistryScaffold Morphing EffortsDrug Resistance +20

Discovery of Imidazo[1,2-<i>a</i>]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

Subramanyam J. Tantry, Shankar D. Markad, Vikas Shinde, +51

Journal of Medicinal Chemistry

Bioorganic ChemistryAntimicrobial ChemotherapyChemical BiologyPharmaceutical ChemistryDrug Resistance +16

Trace Element Profiles in Single Strands of Human Hair Determined by HR-ICP-MS

Kristin Gellein, Syverin Lierhagen, Per Steinar Brevik, +5

Biological Trace Element Research

Trace Element ProfilesMass SpectrometryBiostatisticsAnalytical ChemistryDermatology +4

4-Aminoquinolone Piperidine Amides: Noncovalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity

Maruti Naik, Vaishali Humnabadkar, Subramanyam J. Tantry, +47

Journal of Medicinal Chemistry

Discovery of Pyrazolopyridones as a Novel Class of Noncovalent DprE1 Inhibitor with Potent Anti-Mycobacterial Activity

Manoranjan Panda, Sreekanth A. Ramachandran, Vasanthi Ramachandran, +14

Journal of Medicinal Chemistry

Antimicrobial ChemotherapyPharmaceutical ChemistryPotent Anti-mycobacterial ActivityMtb StrainDrug Resistance +18

Bactericidal Activity and Mechanism of Action of AZD5847, a Novel Oxazolidinone for Treatment of Tuberculosis

V. Balasubramanian, Suresh Solapure, Harini Iyer, +12

Antimicrobial Agents and Chemotherapy

Pulmonary TuberculosisRibosomal SubunitTb DrugsMedicineBactericidal Activity +12