Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

Medicine, Hematology, Oncology +14

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Tsvee Lapidot, Christian Sirard, Josef Vormoor et al. · Nature · 1994 · 4.7K citations

Medicine, Cell Biology, Hematology +14

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

In-Kyung Park, Dalong Qian, Mark J. Kiel et al. · Nature · 2003 · 1.8K citations · Full text

Life Sciences, Cell Biology, Hematology +10

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

Life Sciences, Genetics, Molecular Biology +13

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

Takehiko Kamijo, Jason D. Weber, Gerard P. Zambetti et al. · Proceedings of the National Academy of Sciences · 1998 · 899 citations

Life Sciences, Cell Biology, Molecular Biology +15