Stemness Regulation
Stemness Regulation is a biological mechanism that governs the maintenance, acquisition, and suppression of stem cell properties—such as self-renewal, pluripotency, and differentiation potential—within cancer stem cells through intrinsic signaling pathways and extrinsic microenvironmental cues.
2.8K
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194.7K
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21.9K
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3.1K
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2017–2026
1.8K
Parents
2.8K
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
Fengyan Yu, Herui Yao, Pengcheng Zhu et al. · Cell · 2007 · 1.9K citations · Full text
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
Julie Lessard, Guy Sauvageau · Nature · 2003 · 1.5K citations
MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells
Na Xu, Thales Papagiannakopoulos, Guangjin Pan et al. · Cell · 2009 · 1.1K citations · Full text
Senescence-associated reprogramming promotes cancer stemness
Maja Milanovic, Dorothy Ngo-Yin Fan, Dimitri Belenki et al. · Nature · 2017 · 1.1K citations
Medicine, Cancer Biology, Oncology +12
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Sun Yat-sen University
Guangzhou, China
52 h-index
830 publications
71.2K citations
Harvard University
Cambridge, United States
40 h-index
250 publications
51K citations
Sun Yat-sen University Cancer Center
Guangzhou, China
38 h-index
260 publications
18.1K citations

Howard Hughes Medical Institute
Chevy Chase, United States
35 h-index
102 publications
17.1K citations

University of Hong Kong
Pok Fu Lam, Hong Kong
34 h-index
252 publications
22.9K citations

Shanghai Jiao Tong University
Shanghai, China
34 h-index
361 publications
22K citations

Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
34 h-index
284 publications
20.2K citations
The University of Texas MD Anderson Cancer Center
Houston, United States
33 h-index
343 publications
50.2K citations
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109 publications · 5.8K citations
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83 publications · 8.4K citations
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70 publications · 5.8K citations
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63 publications · 6.3K citations
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74 publications · 4.7K citations
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