Senescence-associated reprogramming promotes cancer stemness

Maja Milanovic, Dorothy Ngo-Yin Fan, Dimitri Belenki, +20

Nature

Tumor BiologyLineage PlasticityStem Cell ResearchCellular SenescenceMedicine +2

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

Jan R. Dörr, Yong Yu, Maja Milanovic, +21

Nature

MedicineCellular SenescenceMetabolic RemodelingAnti-cancer AgentRadiation Oncology +5

AP-1 imprints a reversible transcriptional programme of senescent cells

Ricardo Iván Martínez‐Zamudio, Pierre‐François Roux, José Américo Nabuco Leva Ferreira de Freitas, +9

Nature Cell Biology

Transcriptional RegulationSignaling PathwayAp-1 ImprintsGene ExpressionMedicine +2

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations

Jing Hua, Julia Kase, Jan R. Dörr, +13

Genes & Development

ImmunologyImmune RegulationCell DeathMouse Lymphoma ModelCancer Biology +20

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation

A. Schuetz, Didier Nana, Charlotte Rose, +6

Cellular and Molecular Life Sciences

ChromatinTranscriptional RegulationMolecular RegulationNatural SciencesMolecular Biology +7

The cytokine-induced conformational switch of nuclear factor κB p65 is mediated by p65 phosphorylation

Maja Milanovic, Michael Kracht, M. Lienhard Schmitz

Biochemical Journal

Transcriptional repression of <i>NFKBIA</i> triggers constitutive IKK‐ and proteasome‐independent p65/RelA activation in senescence

Marina Kolesnichenko, Nadine Mikuda, Uta E. Höpken, +16

The EMBO Journal

HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop

Vera V. Saul, Laureano de la Vega, Maja Milanovic, +5

Journal of Molecular Cell Biology

Hipk2 Kinase ActivityFull Hipk2 ActivityAmino AcidsCellular PhysiologySignaling Pathway +16

IFN Consensus Sequence Binding Protein (Icsbp) Is Critical for Eosinophil Development

Maja Milanovic, Grzegorz Terszowski, Daniela Struck, +2

The Journal of Immunology

CD20-Targeting Immunotherapy Promotes Cellular Senescence in B-Cell Lymphoma

J. Henry M. Däbritz, Yong Yu, Maja Milanovic, +6

Molecular Cancer Therapeutics

B-cell LymphomaLymphoid NeoplasiaCancer ImmunosurveillanceLymphoma CellsImmunology +12