Jacqueline J.L. Jacobs

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

Cell Regulation, Cell Division, Genetics +8

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

Jacqueline J.L. Jacobs, Blanca Scheijen, Jan Willem Voncken et al. · Genes & Development · 1999 · 1.1K citations · Full text

Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1

Koji Itahana, Ying Zou, Yoko Itahana et al. · Molecular and Cellular Biology · 2002 · 423 citations · Full text

Cell Proliferation, Cytoskeleton, Cancer Biology +20

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Harveer Dev, Ting-Wei Chiang, Chloé Lescale et al. · Nature Cell Biology · 2018 · 408 citations · Full text

Chromatin, Genome Instability, Medicine +7

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers

Jacqueline J.L. Jacobs, Petra Keblusek, Els C. Robanus-Maandag et al. · Nature Genetics · 2000 · 368 citations

Breast Oncology, Medicine, Pathology +8